Assessment of patterns of pituitary dysfunction after severe traumatic brain injury

Background: Chronic posttraumatic brain injury (TBI) pituitary dysfunction is not a novel concept; nonetheless, it has become increasingly common as result of increased exposure to its causes, namely traffic accidents, sports-related injuries, falls, and injuries sustained during conflicts. The goal this study was identify patterns following severe traumatic injury. Methodology: A cross‑sectional conducted by enrolling 200 patients with TBI. Participants were having history moderate‑to‑severe TBI at least 3 months before enrolment. Pituitary function test done for all determine the frequency dysfunction, number axes deficiencies, which hormone mostly affected. Results: 122 had developed after head trauma, while 78 not. most affected trauma GH in 100 (50%), followed gonadal axis, TSH, finally ACTH, 40 (20%), 21(10.5%), 10 (5%), respectively. We can see that single hormonal defect prevalent abnormality 87 (43.5%), two‑axis 9 (4.5%) only (1.5%) suffered from four deficiencies. Conclusion: more than expected cohort investigated, deficiency being aberration, axis impacted.